Secure agentic AI end-to-end

Next week, RSAC™ Conference celebrates its 35-year anniversary as a forum that brings the security community together to address new challenges and embrace opportunities in our quest to make the world a safer place for all. As we look towards that milestone, agentic AI is reshaping industries rapidly as customers transform to become Frontier Firms —those anchored in intelligence and trust and using agents to elevate human ambition, holistically reimagining their business to achieve their highest aspirations. Our recent research shows that 80% of Fortune 500 companies are already using agents. 1 At the same time, this innovation is happening against a sea change in AI-powered attacks where agents can become “ double agents .” And chief information officers (CIOs), chief information security officers (CISOs), and security decision makers are grappling with the resulting security implications: How do they observe, govern, and secure agents? How do they secure their foundations in this new era? How can they use agentic AI to protect their organization and detect and respond to traditional and emerging threats? The answer starts with trust, and security has always been the root of trust. In this agentic era, security must be woven into, and around, every layer of the AI estate. It must be ambient and autonomous, just like the AI it protects. This is our vision for security as the core primitive of the AI stack. At RSAC 2026, we are delivering on that vision with new purpose-built capabilities designed to help organizations secure agents, secure their foundations, and defend using agents and experts. Fueled by more than 100 trillion daily signals, Microsoft Security helps protect 1.6 million customers, one billion identities, and 24 billion Copilot interactions. 2 Read on to learn how we can help you secure agentic AI. Secure agentic AI with Microsoft Security Secure agents Earlier this month, we announced that Agent 365 will be generally available on May 1. Agent 365—the control plane for agents —gives IT, security, and business teams the visibility and tools they need to observe, secure, and govern agents at scale using the infrastructure you already have and trust. It includes new Microsoft Defender, Entra, and Purview capabilities to help you secure agent access, prevent data oversharing, and defend against emerging threats. Agent 365 is included in Microsoft 365 E7: The Frontier Suite along with Microsoft 365 Copilot, Microsoft Entra Suite, and Microsoft 365 E5, which includes many of the advanced Microsoft Security capabilities below to deliver comprehensive protection for your organization. Learn more about Microsoft Agent 365 Secure your foundations Along with securing agents, we also need to think of securing AI comprehensively. To truly secure agentic AI, we must secure foundations—the systems that agentic AI is built and runs on and the people who are developing and using AI. At RSAC 2026, we are introducing new capabilities to help you gain